Package: BioMark 0.4.5

BioMark: Find Biomarkers in Two-Class Discrimination Problems

Variable selection methods are provided for several classification methods: the lasso/elastic net, PCLDA, PLSDA, and several t-tests. Two approaches for selecting cutoffs can be used, one based on the stability of model coefficients under perturbation, and the other on higher criticism.

Authors:Ron Wehrens, Pietro Franceschi

BioMark_0.4.5.tar.gz
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BioMark.pdf |BioMark.html
BioMark/json (API)
NEWS

# Install 'BioMark' in R:
install.packages('BioMark', repos = c('https://rwehrens.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Datasets:
  • SpikeNeg - Spike-in metabolomics data for apple extracts
  • SpikePos - Spike-in metabolomics data for apple extracts
  • neg.markers - Spike-in metabolomics data for apple extracts
  • pos.markers - Spike-in metabolomics data for apple extracts
  • spikedApples - Metabolomics data on spiked apples

On CRAN:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

2.32 score 21 scripts 340 downloads 41 mentions 12 exports 17 dependencies

Last updated 9 years agofrom:bf21eb0c77. Checks:OK: 3 NOTE: 4. Indexed: yes.

TargetResultDate
Doc / VignettesOKNov 22 2024
R-4.5-winNOTENov 22 2024
R-4.5-linuxNOTENov 22 2024
R-4.4-winNOTENov 22 2024
R-4.4-macNOTENov 22 2024
R-4.3-winOKNov 22 2024
R-4.3-macOKNov 22 2024

Exports:AUCbiom.optionsgen.datagen.data2get.biomget.segmentsHCthreshROCroc.valuescalefunselectiontraceplot

Dependencies:codetoolscorpcorentropyfdrtoolforeachglmnetiteratorslatticeMASSMatrixplsRcppRcppEigensdashapestsurvival

Readme and manuals

Help Manual

Help pageTopics
Auxiliary functions in the biomarker packageaux.biom lasso.coef lasso.stab pcr.coef pcr.stab pls.coef pls.stab pval.pcr pval.plsvip shrinkt.coef shrinkt.stab studentt.coef studentt.stab vip.coef vip.stab
Set or return options for stability-based biomarker selectionbiom.options
Simulate data setsgen.data gen.data2
Get biomarkers discriminating between two classescoef.BMark get.biom print.BMark summary.BMark
Subsampling segmentsget.segments
Biomarker thresholding by Higher CriticismHCthresh
ROC curvesAUC identify.ROC lines.ROC plot.ROC points.ROC print.ROC ROC ROC.default roc.value
Different forms of scalingscalefun
Accessor function to the selected variables of a BioMark objectselection
Spike-in metabolomics data for apple extractsneg.markers pos.markers SpikedApple SpikeNeg SpikePos
Metabolomics data on spiked applesspikedApples
Plot the coefficient or stability trace for the lasso/elastic net biomarker selection.traceplot